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Haas [21] has found that professional amateur sports athletes, whiplash, and polytrauma patients show neurocognitive weakness in the absence of brain injuries, gram negative pathogenesis, infections, cerebrovascular disease, and neurodegeneration. Elevated serum IL-6 has been shown to correlate with multiorgan failure and death in polytrauma patients [22, 23]. Hensler et al. [24], Alexander [25], Gunstad and Suhr [26], and Iverson and Lange [27] reported increased serum concentrations of proinflammatory cytokines, including IL-6, in patients with multiple injuries and a high prevalence of the neurocognitive and behavioural symptoms (see Table 1).

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